Cholesterol oxidase(COD/CHOD)

Cholesterol oxidase (CHOD) e faʻamalosia le laasaga muamua i le cholesterol catabolism.O nisi siama e le fa'ama'i fa'ama'i, pei o Streptomyces e mafai ona fa'aogaina le cholesterol e fai ma puna kaponi.O siama faʻamaʻi, e pei o le Rhodococcus equi, e manaʻomia le CHOD e aʻafia ai le macrophage a le tagata talimalo. CHOD e bifunctional. Cholesterol e muamua faʻamaʻiina i cholest-5-en-3-one i se laasaga e manaʻomia FAD.O le cholest-5-en-3-one ua fa'aisomerized i le cholest-4-en3-one. O le tali fa'aisomerization e ono mafai ona toe fa'afo'i se vaega.O le gaioiga a le CHOD e faʻalagolago i mea faʻaletino o le membrane lea e fusifusia ai le substrate.
CHOD e faʻaaogaina e suʻe ai le cholesterol toto.O le enzyme lona lua e sili ona fa'aaogaina i su'esu'ega pe a uma le glucose oxidase.E maua foi e le CHOD le faʻaogaina i le microanalyse o steroids i faʻataʻitaʻiga o meaʻai ma le faʻavasegaina o 3-ketosteroids mai le 3b-hydroxysteroids. O loʻo suʻesuʻeina laʻau Transgenic e faʻaalia ai le cholesterol oxidase i le taua faasaga i le cotton boll weevil.Cholesterol oxidase ua faʻaaogaina foʻi e fai ma suʻesuʻega mole e faʻamalamalama ai fausaga o sela.