Glucose-6-phosphate dehydrogenase (G6PDH)

Glucose 6 phosphate dehydrogenase (G6PD) deficiency ose tulaga tuufaasolo lea e malepe ai sela mūmū (hemolysis) pe a aafia le tino i ni mea'ai, vaila'au, fa'ama'i po'o le atuatuvale.E tupu pe a misi se tagata pe maualalo le maualuga ole enzyme glucose-6-phosphate dehydrogenase.O lenei enzyme e fesoasoani i sela mūmū e galue lelei.O auga ile taimi ole hemolytic e ono aofia ai le mimi pogisa, vaivai, sesega, vave le tātā o le fatu, le manava, ma le samasama o le pa'u (jaundice).O le faaletonu o le G6PD o loʻo tuʻufaʻatasia i se X-soʻotaʻi faʻasolosolo auala ma faʻamaoniga e sili atu ona taatele i tama (aemaise Aferika Amerika ma i latou mai nisi vaega o Aferika, Asia, ma le Metitirani).E mafua mai i suiga o le kenera ile gene G6PD.

Glucose-6-Phophate Dehydrogenase (G-6-PDH) e aofia ai vaega laiti e lua o le mamafa mole tutusa tutusa.O le faʻasologa o le amino acid o le monomer ua faʻasalalau. G-6-PDH ua faʻaaogaina i suʻega mo nicotinamide adenine dinucleotide ma tissue pyridine nucleotides.G-6-PDH e mafai ona toe fa'agaoioia mai vaifofo fa'ama'i urea.

Glucose 6-phosphate dehydrogenase ose enzyme fa'atulafonoina autu i le laasaga muamua o le auala pentose phosphate.G-6-P-DH faʻamaʻiina le kulukose-6-phosphate i luma o le NADP⁺ e maua ai le 6-phosphogluconate.Polyacrylamide gel electrophoresis, staining gaoioiga, ma anti-fefe G-6-PDH antibody immunoblotting suʻesuʻega ua faʻaalia ai o le G-6-PDH o se glycoprotein.