Tranexamic Acid(1197-18-8)
Fa'amatalaga o oloa
● Tranexamic Acid(1197-18-8)
● CAS Nu.:·1197-18-8
● EINECS Nu.: 356.2222
● MF: C8H15NO2
● Paket: 25Kg/Drum
● Tranexamic acid (TXA) o se vailaʻau e faʻaaogaina e togafitia pe puipuia ai le tele o le tafe toto mai le tele o manuʻa, tafe toto, taotoga, aveese nifo, isumu, ma le mamafa o le maʻi masina.[2][3]E fa'aaogaina fo'i mo le angioedema fa'atupu.[2][4]E ave ile gutu pe tui ile vein.
Faiga o gaioiga
Tranexamic acid o se analog synthetic o le amino acid lysine.E avea o se antifibrinolytic e ala i le toe fa'afo'iina o le fa i le lima nofoaga o le tali atu o le lysine i luga o le plasminogen.O lenei mea e faʻaitiitia ai le liua o le plasminogen i le plasmin, puipuia le faʻaleagaina o le fibrin ma le faʻasaoina o le faʻavae o le fausaga o le matrix fibrin. Tranexamic acid e tusa ma le valu taimi le gaioiga antifibrinolytic o se analog matua, ε-aminocaproic acid. gaoioiga o le plasmin ma le malosi vaivai (IC50 = 87 mM), ma e mafai ona poloka le nofoaga galue o le urokinase plasminogen activator (uPA) ma specificity maualuga (Ki = 2 mM), o se tasi o le maualuga i totonu o serine proteases uma.
Tranexamic acid galuega
O le tranexamic acid e masani ona fa'aaogaina pe a mae'a fa'alavelave matuia.[13]O le Tranexamic acid e fa'aaogaina e puipuia ma togafitia ai le toto gau i tulaga eseese, e pei o taotoga nifo, mamafa toto ma'i masina, ma taotoga e maualuga le lamatiaga o le ma'i toto.
| Mea o le Su'ega | Fa'atonuga ole Pharmacopeial | I'uga o Su'ega | |
| UIGA | Fa'aaliga: Pa'epa'e pe toeititi pa'epa'e, pauta tioata | Pa'epa'e tioata pa'epa'e | |
| Solubility: E mafai ona solu i le vai ma le acetic acid glacial, toetoe lava a le mafai ona solu i le acetone ma le ethanol (96%) | Pasia | ||
| FAATINOGA | Infrared Absorption Spectrophotometry: Ole fusi ole IR o loʻo ogatasi ma le Tranexamic acid CRS | Pasia | |
| TOFOTOGA | pH (2,2.3) | 7.0 〜8.0 | 7.4 |
| Mea Fa'atatau (HPLC2.2.29) | Le mama A≤ 0.1 % | Le iloa | |
| Le mama B≤ 0.2% | 0.03% | ||
| Fa'aleagaC Fa'aleaga le fa'ailoaina≤ 0.10% Fa'aleaga D Isi Fa'aleaga | 0.002% 0.001% Le iloa | ||
| Aofa'iga o mea leaga e le'i fa'ailoaina≤ 0.2% | 0.003% | ||
| Halides Fa'aalia o Chlorides | ≤140ppm | <140ppm | |
| Ma'imau ile Fa'amago | ≤0.5% | 0.026% | |
| Sulphated Ash | ≤0.1% | 0.027% | |
| SU'ESU'EGA | E tatau ona i totonu (fa'amamago) 99.0% 〜101.0% | 100.1% | |
